Tıbbi Sistemler ve Bilişim Yüksek Lisans Programı

Head of Program : Bora Garipcan

Professor : Ahmet Ademoğlu, Burak Güçlü, Albert Güveniş, Mehmed Özkan, Cengizhan Öztürk, Hale Saybaşılı, Yekta Ülgen

Associate Professors : Bora Garipcan

Instructor : Dr. Mehmet Yusuf*

*Part Time

This program aims to prepare life scientists and engineers for the electronic age in healthcare. It is expected to fill a major gap in healthcare management, namely the management of biomedical technologies and emerging e-health applications. Participants to this program will acquire the necessary skills to integrate biomedical, information and communication technologies in order to enhance the existing healthcare processes and conform to international standards. They will learn to purchase the right technologies and manage large scale projects. Participants will concentrate on the following areas depending on their specific interests:

Procurement, calibration and management of biomedical technologies: compliance with ISO-9000 and JCI standards, establishment and management of clinical engineering units.
Systems integration of biomedical, information and communication technologies for developing hospital information systems, picture archival and communication systems, special departmental systems and e-health applications involving communication technologies and medical equipment, medical software and e-health systems development.
Design of clinical trials, database development, design of data entry procedures and statistical analysis of clinical data.

Graduates of this program will be able to pursue career opportunities in the health ministry, healthcare organizations, biomedical equipment manufacturers, medical software companies and pharmaceutical companies. Those with entrepreneurial aspirations will find many opportunities to start a venture in medical software development, systems integration or biomedical equipment distribution.

The program is designed specifically for students with undergraduate background in life sciences, engineering or natural sciences. Acceptance to the program will be based on the following criteria: English proficiency (TOEFL, or IELTS, or BUEPT score) LES or GRE score, Undergraduate Grade Point Average (GPA), letters of reference, letter of intent (statement of purpose) and interview.

Prior knowledge or experience with computing and life sciences is not required but will be considered during the admission process. Special courses are available in order to close the gap between students with different backgrounds.

Students will need to complete 30 credits worth coursework and a non credit term project for graduation. A graduate seminar course is also compulsory.

The program requires at least three semesters of study. Courses will be conducted in the evenings during the week and during the daytime on Saturdays.

The courses will be taught mainly by the faculty members of the Institute of Biomedical Engineering. Some specialty courses will be given by outside experts and faculty from other departments at Bogazici University.

** This program is subject to additional tuition and fees.

The courses of the program are listed below:

Required Courses
MDSI 501 Health Regulations and Standards
MDSI 511 Introduction to Computing and Information Technology *or
Introduction to Health Sciences
MDSI 513 Introduction to Medical Informatics
MDSI 579 Graduate Seminar

* Compulsory for students with no background in computing.

Elective Courses
MDSI 502 Biomedical Technology Management
MDSI 504 Quality Assurance Principles for Medical Systems
MDSI 505 Design of Clinical Trials
MDSI 510 Biostatistics
MDSI 512 Telecommunications, Networks and Information Exchange
MDSI 515 Data Bases and Data Mining for Healthcare
MDSI 516 Biomedical Image Processing
MDSI 517 Object-Oriented Programming
MDSI 518 Clinical Decision Support Systems
MDSI 519 E-Health Technologies
MDSI 531 Biomedical Technologies
MDSI 533 Medical Imaging Systems and PACS
MDSI 581 Special Topics
MDSI 582 Special Topics
MDSI 583 Special Topics
MDSI 584 Special Topics
MDSI 585 Special Topics
MDSI 586 Special Topics

Project
MDSI 590 Research Project

The program is designed specifically for students with undergraduate background in life sciences, engineering or natural sciences.

MEDICAL SYSTEMS AND INFORMATICS GRADUATE PROGRAM

First Semester		Cr
MDSI 501	Health Reg. and Standards	3
MDSI 513	Int. to Med. Inform.	3
MDSI 511	Int.to Com.&Inform. Tech.	3
MDSI 521	Int. to Health Science
-- --	Elective	3
		12

Second Semester		Cr
-- --	Elective	3
-- --	Elective	3
-- --	Elective	3
MDSI 579	Graduate Seminar	0
		9

Third Semester
-- --	Elective	3
-- --	Elective	3
-- --	Elective	3
MDSI 590	Research Project	0
		9

Total: 30 Credits.

COURSES DESCRIPTIONS: MDSI 501 Health Regulations and Standards (3+2+0) 3 ECTS 8
(Sağlıkla İlgili Yönetmelik ve Standartlar)
JCAHO Accreditation Standards, ISO 9000 Quality Standards, NFPA 99 standards for healthcare facilities; guidelines for the design and construction of hospitals and healthcare facilities; an overview of European standardization in the healthcare sector; medical devices regulatory system in Turkey.

MDSI 502 Biomedical Technology Management (3+2+0) 3
(Biyomedikal Teknoloji Yönetimi)
Risk management in healthcare; healthcare hazard control and safety management, medical device related incidents, device economics, basic device failures; life cycle cost analysis, value analysis; the importance of clinical engineering; tools for technology acquisition; preventive maintenance and calibration of medical equipment, clinical equipment management and equipment inclusion criteria; reuse of single use devices; medical device standards and CE marking; compliance with the JCAHO standards.

MDSI 504 Quality Assurance Principles for Medical Systems (3+2+0) 3
(Tıbbî Sistemler için Kalite Güvence İlkeleri)
Introduction to quality assurance concepts, basic probability and statistics, quality indicators and measurement, statistical process control. Reliable design of biomedical equipment, quality function deployment, failure analysis; service quality, calibration programs; quality assurance of medical systems and technologies.

MDSI 505 Design of Clinical Trials (3+2+0) 3 ECTS 7
(Klinik Deneylerin Tasarımı)
Formulating and testing a hypothesis; new chemical entity cycle; overview of ICH (International Conference on Harmonisation ), GCP (Good Clinical Practice); analysis and design of a protocol, CRF (Case Report Form) and a complete trial, comparative review of laws, directives and conventions, ethical standards about clinical trials; SOPs (Standard Operating Procedure), conducting, monitoring and auditing clinical trial processes; data management, reporting and documentation.

MDSI 510 Biostatistics (3+2+0) 3 ECTS 7
(Biyoistatistik)
Descriptive statistics, hypothesis testing, estimation, confidence intervals, t-tests, chi-squared tests, analysis of variance, linear regression, correlation, nonparametric tests.

MDSI 511 Introduction to Information Technology (3+2+0) 3 ECTS 8
(Bilgi Teknolojilerine Giriş)
Binary logic; computer hardware, central processing unit, memory, secondary storage, input/output units, telecommunications and networking, internet; multimedia; operating systems, programming languages; database management systems, spreadsheets, word processing applications, computer security and ethical issues.

MDSI 512 Telecommunications, Networks and Information Exchange (3+2+0) 3
(Telekomunikasyon, Ağlar ve Bilgi Alış Verişi)
The data communications industry, data and voice communications concepts, basic technologies, local area network architectures, hardware, and operating systems. Wide area networking concepts, architectures and services, internetworking, remote access and wireless networking, enterprise networks and the internet, network administration, the network development life cycle, network security; electronic data interchange applications in healthcare, standards.

MDSI 513 Introduction to Medical Informatics (3+2+0) 3 ECTS 8
(Tıbbî Bilişime Giriş)
Overview of health information systems. Basic tools for systems analysis and design, principles of database systems, medical language, coding and classification systems, computer based patient records, hospital information systems, technical choices, information systems in clinical departments, clinical support systems, nursing information systems, health information resources, fundamentals of epidemiology, quality management fundamentals, medical decision support systems, biomedical signal analysis, medical imaging; human-computer interfaces in healthcare, costs and benefits of information systems, security in medical information systems; standards for medical informatics.

MDSI 514 Design and Management of Health Information Systems (3+2+0) 3 ECTS 7
(Sağlık Bilgi Sistemlerinin Tasarımı ve Yönetimi)
Information requirement analysis, data flow diagrams, data dictionaries, process modeling. Designing input and output, database, user interface and data entry procedures; quality assurance through software engineering, implementing the information system, object oriented systems analysis and design. Modeling of health care for information systems development, hospital information systems, technical choices and procurement.

MDSI 515 Data Bases and Data Mining for Healthcare (3+2+0) 3 ECTS 7
(Sağlık Hizmetlerinde Veri Tabanları ve Veri Madenciliği)
Introduction to databases and SQL, data warehouse and OLAP technology, data preprocessing, data mining concepts, characterization and system architectures. Data mining algorithms, association rules, predictive modeling, classification, clustering; data mining in healthcare, privacy, security handling, data access from distributed databases, data integration from multiple healthcare institutions and data mining for decision making. Case studies for hospital administrators, for clinicians and for medical researchers.

MDSI 516 Biomedical Image Processing (3+2+0) 3 ECTS 7
(Biyomedikal Görüntü İşleme)
Image processing applications in medicine; digital images, image quality, Receiver operating curves (ROC) analysis for evaluating diagnostic capability. Image enhancement and restoration, image segmentation and classification. Tomographic reconstruction algorithms; 3-D display of organs; picture archival and communication systems.

MDSI 517 Object-Oriented Programming (3+2+0) 3
(Nesne-Tabanlı Programlama)
Introduction to Java, Java language, class libraries, applet programming, network programming, designing user interfaces, multimedia, multi-user programming, debugging, native methods and libraries.

MDSI 518 Clinical Decision Support Systems (3+2+0) 3 ECTS 7
(Klinik Karar Destekleme Sistemleri)
Development and evaluation of clinical diagnostic decision support systems, legal and ethical issues, mathematical foundations of decision support systems, intelligent systems, expert systems, rule based systems, machine learning methods, data mining, and neural networks; applications of clinical diagnostic decision support systems.

MDSI 519 E-Health Technologies (3+2+0) 3
(E-Sağlık Teknolojileri)
Internet based healthcare delivery systems, conventional and novel telemedicine systems, remote consultation systems and their use in clinical decision making process; tele-surgery, tele-pathology concepts, use of e-health by public health agencies; e-commerce in healthcare, planning, developing, and maintaining Web sites and supporting information systems. Business processes, online payments and international legal, privacy and security issues.

MDSI 521 Introduction to Health Sciences (3+2+0) 3 ECTS 8
(Sağlık Bilimlerine Giriş)
Human body as a control system, cell physiology, blood and body fluids, the heart and circulatory system, respiratory system, nervous system, musculoskeletal system, gastrointestinal system, endocrine system, reproductive system.

MDSI 531 Biomedical Technologies (3+2+0) 3 ECTS 7
(Biyomedikal Teknolojiler)
Introduction to biomedical instrumentation, basic transducer principles, sources of bioelectric potentials, electrodes, the cardiovascular system, cardiovascular measurements. Patient care and monitoring, measurements in the respiratory system, noninvasive diagnostic instrumentation. Instrumentation for sensory measurements and study of behavior. Biotelemetry, instrumentation for the clinical laboratory, medical imaging systems, computers in biomedical instrumentation.

MDSI 533 Medical Imaging Systems and PACS (3+2+0) 3
(Tıbbî Görüntüleme Sistemleri ve PACS)
Principles of radiological imaging, projection radiography, digital radiography, tomography, magnetic resonance imaging, nuclear medicine imaging, ultrasound and microscopic imaging. Picture archiving and communication systems (PACS), components, computer networks and industry standards. Basic image processing methods, image compression and computer assisted diagnosis. Hospital Information Systems (HIS) and Radiology Information Systems (RIS). PACS data management, telemedicine and teleradiology.

MDSI 579 Graduate Seminar (0+2+0) 0 ECTS 1
(Lisansüstü Semineri)
A series of seminars to be given by active experts in the field about practical applications and current issues in medical systems and informatics.

MDSI 581, 582, 583, 584, 585, 586 Special Topics (3+2+0) 3 ECTS 7
(Özel Konular)
Special topics on the most recent advances in medical systems, informatics and systems management selected to suit the individual interests of students and faculty in the program.

MDSI 590 Research Project (0+4+0) 0 ECTS 9
(Araştırma Projesi)
Research in the form of a project in the field of medical systems and informatics under the joint guidance of a faculty member and a representative from the health sector.