CHEM 511 Advanced Organic Chemistry (3+0+0) 3 ECTS 8
(İleri Organik Kimya)
An intensive study of selected advanced topics related to current research in organic chemistry.
CHEM 512 Advanced Physical Chemistry (3+0+0) 3 ECTS 8
(İleri Fiziksel Kimya)
An intensive study of selected advanced topics related to current research in physical chemistry such as thermodynamics, kinetics, spectroscopy, bulk electric and magnetic properties, macromolecular physical chemistry, molecular structure and applied numerical methods.
CHEM 513 Advanced Analytical Chemistry (3+0+0) 3 ECTS 8
(İleri Analitik Kimya)
An intensive survey of selected advanced topics related to current research in analytical chemistry.
CHEM 514 Advanced Inorganic Chemistry (3+0+0) 3 ECTS 8
(İleri Anorganik Kimya)
Elementary structure and stereochemistry, symmetry and group theory, spectroscopy, magnetic resonance, crystallography.
CHEM 515 Advanced Biochemistry (3+0+0) 3 ECTS 8
(İleri Biyokimya)
Carbohydrate metabolism (glycolysis, gluconeogenesis, glycogen metabolism, pentose phosphate pathway). Lipid metabolism (fatty acid synthesis, β-oxidation, triacylglycerol metabolism, cholesterol metabolism, lipoproteins). Nitrogen metabolism (amino acid metabolism, urea cycle, heme metabolism). Regulation and cellular processes (signal transduction, metabolic regulation, immune system biochemistry). Special topics (lipopolysaccharides, photosynthesis).
Prerequisite: consent of instructor
CHEM 520 Polymer Therapeutics (3+0+0) 3 ECTS 8
(Polimer Terapotikler)
An introduction to use of polymers in the medical field: Biocompatible and biodegradable polymers, polymer-drug conjugates, self-assembled polymeric carriers (polymeric micelles, polymer-coated liposomes, nanoparticles, microspheres), interactions of polymers with tissues and cells, pharmacokinetics of polymer therapeutics, targeted polymer therapeutics, stimuli responsive systems, hydrogels.
CHEM 521 Dendrimers: Synthesis and Applications (3+0+0) 3 ECTS 8
(Dendrimerler: Sentez ve Uygulamalar)
Historical development of dendritic macromolecules, structural characteristics of dendrimers vs. linear and branched polymers, classification of dendritic architectures, traditional and modern synthetic methods. Self-assembly of dendrimers, dendrimer-based biomedical applications, molecular-imprinting and detection, dendrimer-based bio-immobilization. Dendrimer-based nanocomposites as sensors, applications in design of light-harvesting devices.
CHEM 522 Advanced Computational Chemistry (2+0+2) 3 ECTS 8
(İleri Hesaplamalı Kimya)
Potential energy surfaces and geometry optimizations, frequency calculations, effect of basis sets, chemical reactions and reactivity calculations, modeling systems in solutions.
CHEM 523 Laser Fundamentals and Applications in Chemistry (3+0+0) 3 ECTS 8
(Lazerlerin Temelleri ve Kimyadaki Uygulamaları)
Atom and molecule interactions with light waves. Laser operation basics. Laser systems. Absorption spectroscopy, LIF, Raman Spectroscopy.
Photodissociation of molecules. Multiphoton excitation and photoionization. Surface reactions and lasers. Environmental, industrial, and
biological applications.
CHEM 524 Chemical Kinetics and Catalysis (3+0+0) 3 ECTS 8
(Kimyasal Kinetik ve Kataliz)
Rates of chemical reactions, kinetics of complex reactions, gas and liquid phase reactions, collision theory, transition state theory, homogeneous and heterogeneous catalysis
CHEM 525 Bioanalytical Chemistry (3+0+0) 3 ECTS 8
(Biyoanalitik Kimya)
Modern techniques for the isolation, purification, and characterization of biomacromolecules (proteins, peptides, polysaccharides, nucleic acids).
Various spectroscopy methods, light scattering, mass spectrometry, chromatography, NMR, PCR, ELISA, Western Blotting, biosensors, lab-on-achip
analysis.
CHEM 526 Ionic Macromolecules (3+0+0) 3 ECTS 8
(İyonik Makromoleküller)
Physicochemical characteristics of ionic macromolecules, polyelectrolytes, proteins, surfactants, and dendrimers. Conformation of neutral polymers and polyelectrolytes in different solvents, Gouy-Chapman theory, counterion condensation, and solubility. Characterization techniques
such as light, neutron and X-ray scattering, rheology, zeta potential, viscosity, osmotic pressure and titration. Behavior of polyelectrolytes in solutions, gels, coacervates. Surface-adsorbed layers and grafted brushes.
CHEM 527 Advanced Characterization Techniques for Batteries (3+0+0) 3 ECTS 8
(Bataryalar için İleri Karakterizasyon Teknikleri)
Advanced characterization techniques for rechargeable battery materials and cells. Ex-situ, in-situ and operando analytical methods. Electrochemical characterization techniques. X-ray diffraction. X-ray photoelectron spectroscopy (XPS). Galvanostatic intermittent titration technique (GITT). Differential capacity analysis (dQ/dV). Synchrotron-based methods. X-ray computed tomography (XCT) for structural and chemical analysis of battery materials and components.
CHEM 528 Energy Sources (3+0+0) 3 ECTS 8
(Enerji Kaynakları)
Energy sources and sustainability, criteria for sustainable energy, geologic limits of fossil fuels, environmental limits of fossil fuels, nuclear energy, nuclear conversion and power plants, nuclear fuels and waste management, solar energy, solar thermal systems, photovoltaic cells, wind energy, biofuels and biomass, hydrogen economy, battery and fuel cells. PEM fuel cells, solid oxide fuel cells.
CHEM 529 Recent Advances in Computational Modeling (3+0+0) 3 ECTS 8
(Hesaplamalı Modellemede Güncel Gelişmeler)
Theory and applications of advanced computational techniques. Ab initio molecular dynamics. Biased molecular dynamics. Metadynamics. Monte Carlo simulations. Enhanced sampling. Umbrella sampling. Transition path sampling.
CHEM 531 Mechanical Properties of Polymers (3+0+0) 3 ECTS 8
(Polimerlerin Mekanik Özellikleri)
Mechanical properties of polymers and typical polymer transitions. Deformation mechanisms; viscous flow, elasticity, rubberlike elasticity and viscoelasticity. Effect of molecular structure and environment on mechanical properties of polymers. Experimental methods used in determination of mechanical properties of polymers including melt flow index, tensile, tear, stress relaxation, creep, impact, fatigue, abrasion, hardness and dynamic mechanical tests together with their ASTM references.
CHEM 533 Synthetic Organic Chemistry (3+0+0) 3 ECTS 8
(Sentetik Organik Kimya)
Synthesis of organic compounds, modern laboratory techniques, oxidation, reduction, condensation, alkylation reactions, separation and purification methods. Six hours of laboratory per week.
CHEM 534 Physical Organic Chemistry (3+0+0) 3 ECTS 8
(Fiziksel Organik Kimya)
Effects of structure, resonance, inductance and medium effects on chemical and physical properties of organic molecules and intermediates, developments in mechanistic pathways.
CHEM 535 Polymer Chemistry (3+0+0) 3 ECTS 8
(Polimer Kimyası)
Introduction to polymers, synthesis; mechanism, reaction rates, chemical reactions of polymers, production of industrially important polymers.
CHEM 536 Structural Polymer Chemistry (3+0+0) 3 ECTS 8
(Yapısal Polimer Kimya)
Physical properties of polymer: phase transitions, solubility, crystallization and crystal structures, viscoelastic behavior; property-structure relationships. Examination of industrial operations such as molding, extrusion, drawing, etc.
CHEM 537 Polymer Characterization (3+0+0) 3 ECTS 8
(Polimer Karakterizasyonu)
Fundamental concepts in polymer analysis and characterization. Sampling and sample preparation. Extraction and analysis of extracts; UV, VIS, IR, NMR and MS. Determination of molecular weights of polmers by functional group analysis, measurements of colligate properties, light scattering, ultracentrifugation and dilute solution viscocity. Fraction of polymers by solubility and size exclusion chromatography (SEC).
CHEM 538 Polymer Applications (3+0+0) 3 ECTS 8
(Polimer Uygulamaları)
Synthesis of some important groups of polymers and their applications: Water soluble polymers and hydrogels from medical to environmental applications. Biodegradable polymer systems for biomedical and biotechnological applications. Conducting polymers for batteries and sensors. Liquid crysttalline polymers for specialized fibers and electro-optical applications, includig displays and information storage. Photopolymers for coating and photoresist applications. Emphasis on the relationship between structure, properties and applications.
CHEM 547 Chemistry of Heterocyclic Compounds (3+0+0) 3 ECTS 8
(Heterosiklik Bileşiklerin Kimyası)
Chemical properties of heterocyclic compounds. Synthesis, reactions and reaction mechanisms of heterocyclic compounds.
CHEM 558 Mass Spectrometry: Principles and Applications (3+0+0) 3 ECTS 8
(Kütle Spektrometrisi: İlke ve Uygulamalar)
Fundamentals and types of mass spectrometry techniques. Different types of ion source and mass analyzer instrumentation, their function, and their application protocols in gas phase molecule chemistry and analysis. Typical fragmentation reactions. Identification of metabolites, synthetic and biopolymers, peptides and sugar oligomers, inorganic clusters. Application to surface analysis of soft and hard surfaces.
CHEM 559 Surface and Colloidal Chemistry (3+0+0) 3 ECTS 8
(Kolloid ve Yüzey Kimyası)
Introduction to surface chemistry and the colloidal state, the liquid-gas and liquid-liquid interfaces, electrical phenomena at interfaces, colloidal solutions, emulsions, foams, aerosols and gels.
CHEM 561 Advanced Nuclear Magnetic Resonance Spectroscopy (3+0+0) 3 ECTS 8
(İleri Nükleer Manyetik Resonans Spektrometresi)
Basic NMR theory and instrumentation, NMR parameters, chemical shift, spin-spin coupling. Analysis of complex spin systems, nuclear overhouser effect, principles of pulse NMR and application on proton and insensitive nuclei such as 13C, 15N, 17O, 19F complex pulse sequences. Two-dimensional NMR (COSY, NOESY, ROSY), dynamic NMR.
CHEM 571 Photochemistry (3+0+0) 3 ECTS 8
(Fotokimya)
Light, waves, atoms and molecules. Electromagnetic radiation, energy levels in atoms, molecular orbitals and electronic states vibrational and rotational energies, potential energy functions, electronic transitions, selection rules, the Frank-Condon principle, light absorption and its physical consequences, characteristics of photochemical reactions, decay and deactivation of excited atoms, diatomic molecules and polyatomic molecules. Light absorption by atoms, primary products case studies, experimental and theoretical selected research topics.
CHEM 579 Graduate Seminar (0+1+0) 0 ECTS 2 Pass/Fail
(Lisansüstü Seminer)
Seminars offered by faculty, guest speakers and/or graduate students designed to widen students' perspectives on specific topics of interest and to expand their range of scientific research techniques and publication ethics.
CHEM 580-599 Special Topics in Chemistry (3+0+0) 3 ECTS 8
(Kimyada Seçme Konular)
Selected topics related to the chemical sciences involving theory, practice and research on current chemical problems.
CHEM 591 M.S. Seminar (0+1+0) 0 ECTS 2 Pass/Fail
(Yüksek Lisans Semineri )
Students give a seminar on a chosen topic of interest (preferably related to their research). A literature survey and a well organized seminar are required.
Prerequisite: Consent of the instructor.
CHEM 601 Current Research Topics (1+0+0) 1 ECTS 2 (Pass/Fail)
(Güncel Araştırma Konuları)
Assessment of the students in current research topics they are guided to follow.
Prerequisite: Consent of the instructor.
CHEM 647 Nanomedicine (3+0+0) 3 ECTS 8
(Nanoilaç)
Cell therapy, gene therapy, diagnostics, radiopharmaceuticals, targeted drug delivery systems, hydrogels.
Prerequisite: CHEM 520 or Consent of Instructor
CHEM 648 Organometallic Chemistry (3+0+0) 3 ECTS 8
(Organometalik Kimya)
Transition metal organometallic chemistry, their methods of synthesis. Theories of bonding and structure, ligands, reactivity, catalysis. Applications of organometallic complexes in organic synthesis and industrial catalysis.
CHEM 657 Molecular Spectroscopy (3+0+0) 3 ECTS 8
(Moleküler Spektroskopi)
Key spectroscopic methods used by chemists and biochemists to analyze the molecular and electronic structure of atoms and molecules by means of electromagnetic radiations, UV/Visible, Infra-Red (IR), Raman, and Rotational spectroscopies. Modern spectroscopy, solar cells and photochemical pollution, and their industrial applications.
CHEM 690 M.S. Thesis ECTS 60
(Yüksek Lisans Tezi)
CHEM 699 Guided Research (2+0+4) 4 ECTS 8
(Yönlendirilmiş Araştırmalar)
Research in the field of chemistry, by arrangement with members of the faculty; guidance of doctoral students towards the preparation and presentation of a research proposal.
CHEM 700 Graduate Seminar (0+1+0) 0 ECTS 2 (Pass/Fail)
(Lisansüstü Seminer)
Seminars offered by faculty, guest speakers and graduate students designed to widen students' perspectives on specific topics of interest and to expand their range of scientific research techniques and publication ethics.
CHEM 790 Ph.D. Thesis ECTS 120
(Doktora Tezi)